| Date | Home | Away | Result |
|---|---|---|---|
| 24/10/25 19:30 | SD Huesca | UD Las Palmas | 1-1 |
| 25/10/25 13:00 | CyD Leonesa | AD Ceuta FC | 0-1 |
| 25/10/25 15:15 | SD Eibar | CD Leganes | 0-0 |
| 25/10/25 15:15 | Albacete Balompie | Cordoba CF | 1-3 |
| 25/10/25 17:30 | FC Granada | FC Cadiz | 0-0 |
| 25/10/25 17:30 | Burgos CF | Real Sociedad B | 1-0 |
| 25/10/25 20:00 | CD Mirandes | Racing Santander | 1-3 |
| 26/10/25 13:00 | FC Malaga | Andorra CF | 4-1 |
| 26/10/25 17:30 | Sporting Gijon | Real Saragossa | 1-0 |
| 26/10/25 17:30 | UD Almeria | CD Castellon | 1-0 |
| 26/10/25 20:00 | Deportivo La Coruna | Real Valladolid | 1-1 |